The teenagers of Disney's most infamous villains return to the Isle of the Lost to recruit a new batch of villainous offspring to join them at Auradon Prep.

When the pressure to be royal becomes too much for Mal, she returns to the Isle of the Lost where her archenemy Uma, Ursula's daughter, has taken her spot as self-proclaimed queen.

A federal agent tracks four people who suddenly seem to possess entirely new personalities, leading to a startling discovery about humanity's future.