When a bachelor party and a bachelorette party cross paths in Vegas, only the best man and maid of honor can save their friends from a night of epic "mistakes."

When two freshmen pledges are accepted into the biggest party frat on campus, they think they have it all. That is, until the assistant dean forces the Alphas to share their house with a sorority or face expulsion from school. Not wanting to see their lifelong dream of becoming Alphas destroyed, the pledges convince the other members of the house to take back what's theirs, waging an epic battle of the sexes to fight for their right to party.